In 1993, a breakthrough new technology, known as CRISPR, gave scientists a path to treat incurable diseases through genetic editing.
In 2016, due to its potential for misuse, the U.S. Intelligence Community designated genetic editing a "Weapon of Mass Destruction and Proliferation."
Global icon Dwayne Johnson headlines the action-adventure Rampage, directed by Brad Peyton.
Johnson stars as primatologist Davis Okoye, a man who keeps people at a distance but shares an unshakable bond with George, the extraordinarily intelligent, incredibly rare albino silverback gorilla who has been in his care since he rescued the young orphan from poachers. But a rogue genetic experiment gone awry mutates this gentle ape into a raging creature of enormous size.
To make matters worse, it’s soon discovered there are other similarly altered animals. As these newly created alpha predators tear across North America, destroying everything in their path, Okoye teams with discredited geneticist Kate Caldwell (Naomie Harris) to secure an antidote, fighting his way through an ever-changing battlefield, not only to halt a global catastrophe but to save the fearsome creature that was once his friend.
Rampage also stars Oscar nominee Naomie Harris (Moonlight), Malin Akerman (TV’s Billions), Jake Lacy (TV’s Girls), Joe Manganiello (TV’s True Blood), and Jeffrey Dean Morgan (TV’s The Walking Dead); as well as P.J. Byrne (The Wolf of Wall Street), Marley Shelton (TV’s Rise), Breanne Hill (TV’s Frontier), Jack Quaid (The Hunger Games: Catching Fire), Matt Gerald (TV’s Daredevil), Jason Liles (Death Note), Demetrius Grosse (TV’s The Brave), and Will Yun Lee (TV’s Hawaii Five-O).
Peyton directed from a screenplay by Ryan Engle and Carlton Cuse & Ryan J. Condal and Adam Sztykiel, story by Ryan Engle.
Rampage was produced by Beau Flynn, John Rickard, Brad Peyton and Hiram Garcia. It marks the third collaboration between Johnson, Peyton, Flynn and Garcia, following the international blockbuster hit San Andreas, Warner Bros.’ highest grossing film of 2015, as well as 2012’s global smash Journey 2: The Mysterious Island. Executive producers were Marcus Viscidi, Dwayne Johnson, Dany Garcia, Jeff Fierson, Toby Emmerich, Richard Brener and Michael Disco.
The creative team includes director of photography Jaron Presant, production designer Barry Chusid, editors Jim May and Bob Ducsay, and costume designer Melissa Bruning. The music is composed by Andrew Lockington, who created the scores for San Andreas and Journey 2: The Mysterious Island. Serving as co-producers were Wendy Jacobson, Josh Mack and Dana Robin.
The Rampage creatures were brought to life by acclaimed VFX supervisor Colin Strause, with five-time Academy Award-winning visual effects company Weta Digital.
A New Line Cinema presentation, in association with ASAP Entertainment, a Wrigley Pictures / F.P.C. / Seven Bucks Productions, a Brad Peyton Film, Rampage will be distributed in 2D and 3D in select theaters, and IMAX, by Warner Bros. Pictures, a Warner Bros. Entertainment Company. This film has been rated PG-13.